vanillic acid biological activity

Vanillic acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice. MSDS/SDS Database Search | This is consistent with the repeated findings of increased Fluoro-Dopa (F-Dopa) uptake in the striatum of patients with schizophrenia, which measures dopamine synthesis by the dopamine synthesizing enzyme l-amino-acid decarboxylase (Frankle, 2007). The extract has antioxidant activity and protects the liver from hepatotoxin-inducing liver fibrosis.105 Specifically, treatment (10 mg/kg body weight by i.p.

Caffeic acid is sequentially degraded to rotocatechuic p acid, 4-vinylcatechol, vanillyl alcohol, vanillic acid, dihydro-caffeic acid, 4-ethylcatechol, m-hydroxy-phenyl Design, synthesis, biological evaluation and molecular modeling of novel 1,3,4-oxadiazole derivatives based on Vanillic acid as potential immunosuppressive agents. It is known that lignin-derived phenolic compounds (vanillin, ferulic acid, benzoate, 4-hydroxybenzoate, vanillate, and phenol) are the main growth inhibitors in lignocellulosic hydrolyzates for microbial fermentation.95,96 Surprisingly, at least for acid production under oxygen deprivation conditions, C. glutamicum is not affected by these substances, displaying a high tolerance to several phenolic inhibitors.97 In addition, it has an impressive ability to utilize aromatic compounds, making it particularly interesting in the perspective of a bioprocess based on agro-wastes hydrolyzates, such as rice straw. All experiments are performed independently in triplicate[2]. Few recent studies exhibited robust antibacterial activity of VA against several pathogen microorganisms. L. plantarum cells were grown in the presence of several hydroxybenzoic acids, such as gallic, syringic, p-hydroxybenzoic, protocatechuic, and vanillic acids. Following this, the cells are incubated with MTT solution for another 2-4 h at 37°C.

The statements, opinions and data contained in the journals are solely HHS This site needs JavaScript to work properly. Epub 2012 Jan 25.

Sci Rep. 2017 Jan 18;7:40753. Expert Opin Ther Pat. MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. J Nat Prod. It is a monohydroxybenzoic acid and a methoxybenzoic acid.It is a conjugate acid of a vanillate. The subject of biological activity research is also the phenolic extract of olive oil. Vanillic acid is a potent free radical scavenger, thus, it exerts protective effects in isoproterenol induced cardiotoxic rats due to its free radical scavenging, antioxidant and anti-inflammatory properties. The hepatoprotective effects of syringic acid and vanillic acid have been analyzed in CCl4-induced liver injury in mice.106 Following treatment of mice with syringic acid and vanillic acid, Azan-stained liver sections exhibit reduced collagen accumulation and hydroxyproline content.

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